New York Governor Andrew Cuomo is facing increased pressure to quit after the state's senators joined calls for him to resign following allegations of sexual misconduct.
Fellow Democrats Chuck Schumer and Kirsten Gillibrand said Mr Cuomo had "lost the confidence" of New Yorkers.
Five women have accused Mr Cuomo of sexual misconduct, including unwanted kissing, and a sixth alleged assault.
Mr Cuomo has denied all of the allegations against him.
He has defied calls to resign from Democrats.
"I did not do what has been alleged," Mr Cuomo said. "I never harassed anyone, I never assaulted anyone, I never abused anyone."
In their statement, Mr Schumer, who is also the Senate majority leader, and Ms Gillibrand, said: "Due to the multiple, credible sexual harassment and misconduct allegations, it is clear that Governor Cuomo has lost the confidence of his governing partners and the people of New York. Governor Cuomo should resign."
Earlier, New York Congresswoman Alexandria Ocasio-Cortez and Congressman Jamaal Bowman also released a joint statement that said, "we believe these women, we believe the reporting, we believe the Attorney General, and we believe the fifty-five members of the New York State legislature," referring to a group of legislators who have called on Mr Cuomo to resign.
"Governor Cuomo can no longer effectively lead in the face of so many challenges", the statement said.
New York City Mayor Bill de Blasio, a long-time political rival of Democrat Governor Cuomo, told reporters on Thursday that the latest allegation is "disgusting to me, and he can no longer serve as governor."
Mr Cuomo, whose term in office comes to an end in 2022, was last year praised for his handling of the Covid epidemic in his state. However, this year he has been accused of obscuring the scale of coronavirus deaths in the state's nursing homes.
On Thursday, New York State Assembly Speaker Carl Heastie said he had given the go-ahead for an "impeachment investigation" into the allegations made against Mr Cuomo. The investigation, which will interview witnesses and look at evidence, would be the first step towards impeachment.
Mr Cuomo has said he would wait for the results of an independent investigation into the allegations, which is being overseen by the New York's attorney general Letitia James.